The most appropriate management for this woman with diverticulitis is treatment with oral antibiotics with home discharge and close clinical follow-up. The therapeutic approach to diverticulitis is dictated by patient-related factors, the severity of clinical features, and the ability to tolerate oral intake. In a healthy, immunocompetent patient with mild symptoms, outpatient therapy is appropriate and should consist of a liquid diet, oral antimicrobial agents that cover colonic organisms and include anaerobic coverage (such as ciprofloxacin and metronidazole), and as-needed analgesia. Close follow-up is warranted to detect any deterioration as soon as possible. For older, frail, sicker patients, and in those with potential complications of diverticulitis (such as peritonitis or fistula formation), hospitalization is recommended for administration of intravenous antimicrobial agents and observation. This patient with diverticulitis has mild symptoms and is otherwise
healthy. She is able to maintain oral intake and can therefore be managed as an outpatient with oral antibiotics and close follow-up.