Albumin is a protein normally found in blood. Solutions of human albumin can be given to patients through their veins (intravenously). These products are expensive and sometimes difficult to get. Albumin is usually given to people who are very ill, such as those who have severe burns, serious trauma, major surgery, shock, life-threatening infections, or liver failure. Treatment with albumin may increase blood protein levels, circulating blood volume, and blood pressure when they are abnormally low. However, whether albumin improves or worsens the chance of survival of critically ill patients is controversial.