Giant-cell arteritis (GCA) and polymyalgia rheumatica (PMR) are two seemingly related inflammatory disorders. About 50% of people with GCA also have PMR; about 10% of people with PMR also have GCA. The causes of these disorders are unknown. They occur most often in people older than 50 years of age and increasingly often with advancing age. Both disorders are seen more often in women and in white persons. In GCA, also known as temporal arteritis or granulomatous arteritis, certain arteries, particularly those in the head, neck, and arms, become inflamed and swollen. The inflammation causes narrowed arteries and may result in complete blockage. Symptoms of GCA include headaches, scalp tenderness, and jaw pain while chewing. Less common symptoms include visual loss, sore throat, dry cough, and pain in the arms and legs. In PMR, inflammation occurs throughout the body. Symptoms include weight loss; fever; muscle pain; and neck, shoulder, and hip stiffness. Both disorders respond well to corticosteroids, such as prednisone. Many patients remain free of disease when corticosteroid therapy is stopped after several years.