Doctors should counsel all obese patients about diet and exercise. Doctors and patients should identify goals for weight loss, blood pressure, and blood sugar. Doctors and obese patients may consider obesity drugs when patients are unable to reach their goals with diet and exercise alone. Patients should understand the potential side effects and the lack of long-term studies of the effectiveness and safety of obesity drugs. Available obesity drugs include sibutramine, orlistat, phentermine, diethylpropion, fluoxetine, and bupropion. Doctors and patients should discuss the side effect profile of each medication to determine which drug would be best for an individual patient.