0
Summaries for Patients |

The Effect of Virgin and Refined Olive Oils on Heart Disease Risk Factors FREE

[+] Article and Author Information

The summary below is from the full report titled “The Effect of Polyphenols in Olive Oil on Heart Disease Risk Factors. A Randomized Trial.” It is in the 5 September 2006 issue of Annals of Internal Medicine (volume 145, pages 333-341). The authors are M.-I. Covas, K. Nyyssönen, H.E. Poulsen, J. Kaikkonen, H.-J.F. Zunft, H. Kiesewetter, A. Gaddi, R. de la Torre, J. Mursu, H. Bäumler, S. Nascetti, J.T. Salonen, M. Fitó, J. Virtanen, and J. Marrugat, for the EUROLIVE Study Group.


Ann Intern Med. 2006;145(5):I-53. doi:10.7326/0003-4819-145-5-200609050-00002
Text Size: A A A

What is the problem and what is known about it so far?

A Mediterranean diet is an approach to eating that includes food choices common among people in countries around the Mediterranean Sea. The main fat in the Mediterranean diet is olive oil. The Mediterranean diet also includes fish, vegetables, fruits, whole grains, and nuts. Research has shown a strong connection between Mediterranean diets and lower rates of heart disease. Most researchers believe that the most important health-promoting substance in olive oil is oleic acid, which is a monounsaturated fatty acid. People want to know whether other substances in olive oil also promote health. Researchers think that polyphenol might be another health-promoting substance in olive oil. Virgin olive oil comes from the first pressing of olives. Refined olive oil comes from later pressings. Virgin olive oil has higher amounts of polyphenols than refined olive oil. If the amount of polyphenol in olive oil was important to health, people might prefer to use olive oil that was rich in polyphenols.

Why did the researchers do this particular study?

To determine whether olive oil containing different amounts of polyphenols affected risk factors for heart disease.

Who was studied?

200 healthy men 20 to 60 years of age who lived in 1 of 6 European cities.

How was the study done?

The researchers compared virgin olive oil (high level of polyphenols), refined olive oil (low level of polyphenols), and a mixture of equal amounts of the 2 olive oils (medium level of polyphenols). Each participant consumed about a tablespoon of one of the olive oils each day for 3 weeks. Over the course of the study, each participant consumed each of the 3 olive oils for a 3-week period. The researchers took blood samples to measure cholesterol levels and other chemicals before and after each 3-week period and compared the results after each type of olive oil.

What did the researchers find?

Virgin olive oil (high in polyphenols) increases the level of high-density lipoprotein cholesterol (“good cholesterol”) the most. It also increases the body level of substances that prevent a chemical reaction (oxidation) that may damage low-density lipoprotein cholesterol (“bad cholesterol”) and make it more likely to promote clots in blood vessels that can lead to heart disease.

What were the limitations of the study?

The study was too brief to determine whether consuming olive oil that contained different amounts of polyphenols changed people's risk for heart disease events.

What are the implications of the study?

Virgin olive oil seems to have a bigger effect on health-promoting substances in the body than refined olive oil. More research is needed to find out whether people who use virgin olive oil have a lower chance of developing heart disease than people who use refined olive oil.

Figures

Tables

References

Letters

NOTE:
Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).

Comments

Submit a Comment
Submit a Comment

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.

Toolkit

Want to Subscribe?

Learn more about subscription options

Advertisement
Related Articles
Topic Collections
PubMed Articles

Want to Subscribe?

Learn more about subscription options

Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.
(Required)
(Required)