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"Mesenteric Vascular Insufficiency" in Myocardial Infarction, Cardiac Failure, Cardiac Arrhythmias, and Shock States.

E. Corday, M.D., F.A.C.P.; D. W. Irving, M.D.; H. Gold, M.D., (Assoc.); H. Bernstein, M.D.; and J. H. Williams, M.D.
Ann Intern Med. 1961;54(5):1033. doi:10.7326/0003-4819-54-5-1033_1
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Experimental and clinical evidence will be presented to explain ischemic changes in the gastrointestinal tract resulting from remote extra-mesenteric circulatory disturbances such as hemorrhagic and traumatic shock, arrhythmias, myocardial infarction, and cardiac decompensation. The blood flow of the mesenteric circulation was measured during the various pathological states with the new accurate electromagnetic flowmeter and electronic integrator-computer. The mesenteric circulation decreases markedly during shock states, cardiac arrhythmias, and congestive heart failure. The resistance of the mesenteric circulation increases considerably due to a vasoconstriction. This results in ischemia and necrosis of the gastrointestinal tract. Findings at autopsy have been correlated with direct

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