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Observations on Steatorrhea Associated with Gastric Hypersecretion and Pancreatic Islet Cell Neoplasm.

W. S. Haubrich, M.D., (Assoc.); F. S. O'Neil, M.D.; and M. A. Block, M.D.
Ann Intern Med. 1961;54(5):1048-1049. doi:10.7326/0003-4819-54-5-1048_2
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Of the reported cases of pancreatic islet cell tumor associated with gastric hypersecretion (Zollinger-Ellison syndrome), about one-third mention diarrhea as a prominent symptom. A history of diarrhea was elicited in all four patients exhibiting this syndrome at The Henry Ford Hospital within the past three years. One of these patients, who had neither symptoms nor signs of peptic ulcer disease, sought medical care primarily because of frank steatorrhea, weight loss, and progressive weakness. This patient provided an opportunity for the clinical and laboratory investigation of steatorrhea in this syndrome and its response to treatment.

Stomach aspiration yielded a prodigious volume


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