The full content of Annals is available to subscribers

Subscribe/Learn More  >
Letters |

Successful Treatment of Antineutrophil Cytoplasmic Antibody–Associated Vasculitis With Eicosapentaenoic Acid

Junichi Hirahashi, MD, PhD; Airi Jo, MD; Kohei Ueda, MD; Akihiro Tojo, MD, PhD; and Toshiro Fujita, MD, PhD
[+] Article, Author, and Disclosure Information

From Graduate School of Medicine, The University of Tokyo, 1138655 Tokyo, Japan.

Acknowledgment: The authors thank Makoto Arita and Keiichi Hishikawa for pharmacologic assistance; Masaomi Nangaku and George Seki for supervision and critical reading of the manuscript; and Ai Furuta for a vigorous clinical practice.

Grant Support: This work was supported in part by grants from the Ministry of Health, Labour and Welfare of Japan.

Potential Conflicts of Interest: The authors have applied for patents for the use of EPA to treat ANCA-associated vasculitis.

Ann Intern Med. 2012;156(10):755-756. doi:10.7326/0003-4819-156-10-201205150-00023
Text Size: A A A


Grahic Jump Location
Figure 1.

Renal biopsy specimen.

Glomerulus with a fibrocellular crescent (periodic acid–Schiff stain; original magnification, ×400).

Grahic Jump Location
Grahic Jump Location
Figure 2.

Clinical course of renal function.

To convert serum creatinine levels to µmol/L, multiply by 88.4. ANCA = antineutrophil cytoplasmic antibody; anti-MPO = antimyeloperoxidase antibody; EPA = eicosapentaenoic acid; ND = not determined.

Grahic Jump Location




Citing articles are presented as examples only. In non-demo SCM6 implementation, integration with CrossRef’s "Cited By" API will populate this tab (http://www.crossref.org/citedby.html).


Submit a Comment/Letter
Submit a Comment/Letter

Summary for Patients

Clinical Slide Sets

Terms of Use

The In the Clinic® slide sets are owned and copyrighted by the American College of Physicians (ACP). All text, graphics, trademarks, and other intellectual property incorporated into the slide sets remain the sole and exclusive property of the ACP. The slide sets may be used only by the person who downloads or purchases them and only for the purpose of presenting them during not-for-profit educational activities. Users may incorporate the entire slide set or selected individual slides into their own teaching presentations but may not alter the content of the slides in any way or remove the ACP copyright notice. Users may make print copies for use as hand-outs for the audience the user is personally addressing but may not otherwise reproduce or distribute the slides by any means or media, including but not limited to sending them as e-mail attachments, posting them on Internet or Intranet sites, publishing them in meeting proceedings, or making them available for sale or distribution in any unauthorized form, without the express written permission of the ACP. Unauthorized use of the In the Clinic slide sets will constitute copyright infringement.


Buy Now for $32.00

to gain full access to the content and tools.

Want to Subscribe?

Learn more about subscription options

Forgot your password?
Enter your username and email address. We'll send you a reminder to the email address on record.