The screening literature stresses a difference between mass screening, in which large numbers of men are tested at an event, and screening within the physician–patient relationship. Much of my own concern about prostate cancer screening has been with mass screenings that mislead men to believe that screening can only help them. Over the past 20 years, celebrities, athletes, politicians, and prostate cancer survivor groups have endorsed screening. Mass screening is commonly conducted in shopping malls, churches, and community centers; at conventions and state fairs; and even in vans parked in grocery store parking lots. Hospitals, medical practices, fraternities, politicians, radio stations, television channels, and even an adult diaper manufacturer have sponsored mass prostate cancer screenings. Promotions for these events frequently discuss the high proportion of men with screen-detected tumors surviving 5 years and sometimes claim that screening saves lives. They never mention the potential harms of screening. Many well-meaning persons have supported screening activities and chose not to listen or believe those who have urged caution about screening. Mass screening is also a lucrative business. As Upton Sinclair once said, “It is difficult to get a man to understand something, when his salary depends on his not understanding it” (8).