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Editorials |

Probability, Uncertainty, and Prostate Cancer

John Concato, MD, MPH
[+] Article and Author Information

From Veterans Affairs Connecticut Healthcare System and Yale University, West Haven and New Haven, Connecticut.

Potential Conflicts of Interest: None disclosed. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M12-2994.

Requests for Single Reprints: John Concato, MD, MPH, Clinical Epidemiology Research Center, Veterans Affairs Connecticut Healthcare System, Mailcode 151B, Building 35A, West Haven, CT 06516; e-mail, john.concato@yale.edu.


Ann Intern Med. 2013;158(3):211-212. doi:10.7326/0003-4819-158-3-201302050-00012
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Although recommendations on the optimal approach to prostate cancer screening are conflicting and controversial, screening with PSA has been adopted widely. In this issue, Gulati and colleagues provide a simulation model that estimates PSA trajectory and disease progression under 35 screening strategies. The editorialist discusses PSA-based prostate cancer screening and the study's findings.

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