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Computed Tomography Screening for Lung Cancer: What Is a Positive Screen?

Stephen Lam, MD; Annette McWilliams, MB; John Mayo, MD; and Martin Tammemagi, PhD
[+] Article, Author, and Disclosure Information

From British Columbia Cancer Agency, Vancouver, British Columbia, Canada; Vancouver General Hospital, Vancouver, British Columbia, Canada; and Brock University, St. Catharines, Ontario, Canada.

Potential Conflicts of Interest: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M13-0085.

Requests for Single Reprints: Stephen Lam, MD, British Columbia Cancer Agency, 675 West 10th Avenue, Vancouver, British Columbia V5Z 1L3, Canada; e-mail, slam2@bccancer.bc.ca.

Current Author Addresses: Drs. Lam and McWilliams: Department of Integrative Oncology, British Columbia Cancer Agency, 675 West 10th Avenue, Vancouver, British Columbia V5Z 1L3, Canada.

Dr. Mayo: Department of Radiology, Vancouver General Hospital, 899 West 12 Avenue, Vancouver, British Columbia V5Z 1M9, Canada.

Dr. Tammemagi: Department of Community Health Sciences, Brock University, Walker Complex-Academic South, Room 306, 500 Glenridge Avenue, St. Catharines, Ontario L2S 3A1, Canada.

Ann Intern Med. 2013;158(4):289-290. doi:10.7326/0003-4819-158-4-201302190-00011
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In this issue, Henschke and colleagues examined the tradeoff between a larger threshold for nodule size to define a positive lung cancer screen on CT and the risk for delayed diagnoses. The editorialists discuss the study and its findings and call for sophisticated modeling studies to define the tradeoffs of different thresholds for a positive CT screen for lung cancer.

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