Hospitals are now faced with the challenge of reevaluating their current transitional care practices in order to reduce 30-day readmission rates. Although emphasizing readmissions may have good face validity, we believe that policymakers' focus on 30-day readmissions is problematic. Only a small proportion (approximately 20% from published studies) (78) of readmissions at 30 days are probably preventable, and much of what drives hospital readmission rates are patient- and community-level factors, such as mental illness, poor social support, and poverty, that are well outside the hospital's control (79–80). Furthermore, high readmission rates can be the result of low mortality rates, improved access to hospital care, and high admission rates (81) and therefore may not always represent care transitions failures. Because there are currently no reliable methods to predict an individual patient's readmission risk (82), hospitals face significant difficulties in determining which patients should be targeted for transitional care interventions. Finally, because hospitals are expending resources on reducing readmissions, they may not be able to address other, more pressing patient safety issues. In this context, our finding that only a few resource-intensive interventions seem to reduce readmission rates is especially problematic.