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Editorials |

Statin Discontinuation and Intolerance: The Challenge of Lifelong Therapy

Scott M. Grundy, MD, PhD
[+] Article, Author, and Disclosure Information

From Center for Human Nutrition, University of Texas Southwestern Medical Center, Dallas, Texas.

Potential Conflicts of Interest: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M13-0413.

Requests for Single Reprints: Scott M. Grundy, MD, PhD, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Suite Y3.206, Dallas, TX 75390-9052; e-mail, scott.grundy@utsouthwestern.edu.

Ann Intern Med. 2013;158(7):562-563. doi:10.7326/0003-4819-158-7-201304020-00010
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Statins are among the most widely prescribed drugs, but discontinuation rates are relatively high. In this issue, Zhang and colleagues used electronic health records to explore statin discontinuations among patients in 1 hospital system and found that many patients who discontinue statins could tolerate them if rechallenged. The editorialist discusses the study and advocates for better strategies to promote statin adherence.

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