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Ideas and Opinions |

Acute HIV-1 Infection: A Call to Action

Mathias Lichterfeld, MD, PhD; and Eric S. Rosenberg, MD
[+] Article, Author, and Disclosure Information

From Massachusetts General Hospital, Boston, Massachusetts.

Grant Support: Dr. Lichterfeld is supported by grants AI098487 and AI093203 from the National Institutes of Health. Dr. Rosenberg is supported by grant AI071915 from the National Institutes of Health.

Potential Conflicts of Interest: None disclosed. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M13-0403.

Requests for Single Reprints: Eric S. Rosenberg, MD, Massachusetts General Hospital, Infectious Disease Division, Gray J-504, 55 Fruit Street, Boston, MA 02114; e-mail, erosenberg1@partners.org.

Current Author Addresses: Drs. Lichterfeld and Rosenberg: Massachusetts General Hospital, Infectious Disease Division, Gray J-504, 55 Fruit Street, Boston, MA 02114.

Author Contributions: Conception and design: E.S. Rosenberg.

Drafting of the article: M. Lichterfeld, E.S. Rosenberg.

Critical revision of the article for important intellectual content: E.S. Rosenberg.

Final approval of the article: M. Lichterfeld, E.S. Rosenberg.

Ann Intern Med. 2013;159(6):425-427. doi:10.7326/0003-4819-159-6-201309170-00010
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Diagnosis of acute HIV-1 infection is infrequently considered and rarely made, but an estimated 50 000 persons in the United States are newly infected each year. This commentary discusses the diagnosis and treatment of this disease. The authors believe that making the diagnosis, counseling patients about their diagnosis, and considering therapy to prevent virus transmission should serve as a “call to action” in managing patients with acute HIV-1.


hiv ; hiv-1 infection

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HIV diagnostic algorithm.

Adapted from the Clinical and Laboratory Standards Institute, 2011 (Criteria for Laboratory Testing and Diagnosis of Human Immunodeficiency Virus Infection; Approved Guideline, Document M53-A).

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