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Ideas and Opinions |

HIV Cure Research: Expanding the Ethical Considerations

Jeremy Sugarman, MD, MPH, MA
[+] Article, Author, and Disclosure Information

This article was published at www.annals.org on 13 August 2013.

From Berman Institute of Bioethics, School of Medicine, and Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland.

Some of the ideas described in this article were presented at the International AIDS Society Symposium, “Toward an HIV Cure,” in Kuala Lumpur, Malaysia, on 30 June 2013.

Grant Support: In part by National Institute of Allergy and Infectious Diseases, National Institute of Drug Abuse, and National Institute of Mental Health under cooperative agreement UM1AI068619 to the HIV Prevention Trials Network, and the Johns Hopkins Center for AIDS Research, which is funded by the National Institutes of Health (grant 1P30AI094189).

Potential Conflicts of Interest: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M13-1696.

Requests for Single Reprints: Jeremy Sugarman, MD, MPH, MA, Johns Hopkins Berman Institute of Bioethics, 1809 Ashland Avenue, Baltimore, MD 21205; e-mail, jsugarman@jhu.edu.

Author Contributions: Conception and design: J. Sugarman.

Drafting of the article: J. Sugarman.

Critical revision of the article for important intellectual content: J. Sugarman.

Final approval of the article: J. Sugarman.

Ann Intern Med. 2013;159(7):490-491. doi:10.7326/0003-4819-159-7-201310010-00694
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Mounting evidence is fueling excitement over the possibility of curing HIV infection. Research aimed at eliminating the need for continuous antiretroviral therapy includes a range of approaches, from bone marrow transplantation and aggressive early treatment of HIV infection to withdrawal of antiretroviral therapy to permit the killing of HIV in biological reservoirs. This commentary discusses the complex ethical issues associated with such research.


hiv ; ethics

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