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ACP Journal Club |

Pooled RCTs: Atorvastatin did not increase renal-related serious adverse events

Ann Intern Med. 2014;161(8):JC8. doi:10.7326/0003-4819-161-8-201410210-02008
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Even statins reduce progression of CKD to ESRD
Posted on October 24, 2014
Gauranga Dhar
Bangladesh Institute of Family Medicine and Research
Conflict of Interest: None Declared
This is a very good RCT and good message for the physician who hesitate prescribing statins for its’ questionable renal adverse effects. Patients with early stages (specifically G3a – G3b or A2 – A3 or in combination) of CKD are in increased risk for CV events even in normolipidemic stages. Due to pleiotropic effects, statins reduce CV event risk as well as reduce progression of CKD along with ezetimibe (SHARP).
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