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Painful Diabetic Neuropathy: Many Similarly Effective Therapies With Widely Dissimilar CostsPainful Diabetic Neuropathy

Brian C. Callaghan, MD, MS; and Eva L. Feldman, MD, PhD
[+] Article, Author, and Disclosure Information

From University of Michigan, Ann Arbor, Michigan.

Financial Support: Dr. Callaghan is supported by the Katherine Rayner Program, the Taubman Medical Institute, and the National Institutes of Health/National Institute of Neurological Disorders and Stroke K23 award. Dr. Feldman is supported by the Taubman Medical Institute and National Institute of Neurological Disorders grants DP3DK094292 and R24 082841.

Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M14-2157.

Requests for Single Reprints: Brian C. Callaghan, MD, MS, A. Alfred Taubman Biomedical Science Research Building, 109 Zina Pitcher Place, 4021 BSRB, Ann Arbor, MI 48104; e-mail, bcallagh@med.umich.edu.

Current Author Addresses: Drs. Callaghan and Feldman: A. Alfred Taubman Biomedical Science Research Building, 109 Zina Pitcher Place, 4021 BSRB, Ann Arbor, MI 48104.

Ann Intern Med. 2014;161(9):674-675. doi:10.7326/M14-2157
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In this issue, Griebeler and colleagues' umbrella systematic review and network meta-analysis evaluates the comparative effectiveness of oral and topical analgesics for diabetic neuropathy. The editorialists discuss how patient comorbid conditions, potential adverse effects, and cost can help physicians decide which medications to prescribe until more evidence is available.

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