Criteria for sofosbuvir coverage based on the following categories were recorded: liver disease stage, HIV co-infection, prescriber type, and drug or alcohol use. For criteria about liver disease staging, data were collected on the level of fibrosis required for reimbursement (either none indicated, Meta-Analysis of Histologic Data in Viral Hepatitis [METAVIR] fibrosis stage F2 or higher, or F3 or F4), eligibility for persons with decompensated cirrhosis, and whether a liver biopsy was mandatory to provide evidence of advanced fibrosis. For criteria about HIV co-infection, data were collected on whether HIV status needed to be documented, and if positive, whether the patient had to be receiving antiretroviral therapy (ART) or have suppressed HIV RNA levels. For prescriber type, data were collected on whether the prescriber had to be a specialist (gastroenterology, hepatology, infectious diseases, or liver transplantation) or whether treatment decisions needed to be made in consultation with a specialist. For criteria about drug or alcohol use, data were collected on whether there were any substance-related access criteria, and if so, whether drug or alcohol counseling was required, whether patients had to be evaluated for drug and/or alcohol dependence, whether a period of abstinence was required (1, 3, 6, or 12 months) before sofosbuvir therapy, and whether drug or alcohol testing and/or treatment was required before sofosbuvir therapy.