Recommended pneumococcal vaccine schedule and intervals, by age, health condition, and other risks.
The dashed line represents the interval between the two PPSV23 doses. PCV13 = 13-valent pneumococcal conjugate vaccine; PPSV23 = 23-valent pneumococcal polysaccharide vaccine.
* Immunocompromising conditions are defined as congenital or acquired immunodeficiency (including B- or T-lymphocyte deficiency, complement deficiencies, and phagocytic disorders excluding chronic granulomatous disease), HIV infection, chronic renal failure, nephrotic syndrome, leukemia, lymphoma, Hodgkin disease, generalized malignancy, multiple myeloma, solid organ transplant, and iatrogenic immunosuppression (including long-term systemic corticosteroids and radiation therapy).
† Anatomical or functional asplenia is defined as sickle cell disease and other hemoglobinopathies, congenital or acquired asplenia, splenic dysfunction, and splenectomy.
‡ Chronic health conditions are defined as chronic heart disease (including congestive heart failure and cardiomyopathies, excluding hypertension), chronic lung disease (including chronic obstructive lung disease, emphysema, and asthma), chronic liver disease (including cirrhosis), chronic alcoholism, or diabetes mellitus.
§ Administer PPSV23 as soon as possible if the 6- to 12-month time window has passed. Reproduced from Reference (3).