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Striking the Right Balance in Heart FailureStriking the Right Balance in Heart Failure

Monica R. Shah, MD; and Michael S. Lauer, MD
[+] Article, Author, and Disclosure Information

This article was published at www.annals.org on 22 December 2015.

From the National Heart, Lung, and Blood Institute, Bethesda, Maryland.

Disclaimer: The opinions expressed here are those of the authors and do not reflect the official positions or opinions of the National Heart, Lung, and Blood Institute or the National Institutes of Health.

Acknowledgment: The authors thank Dr. Eugene Braunwald for his helpful review and comments.

Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M15-2587.

Requests for Single Reprints: Monica R. Shah, MD, Division of Cardiovascular Sciences of the National Heart, Lung, and Blood Institute, 6701 Rockledge Drive, Room 8174, Bethesda, MD 20892-7956; e-mail, shahmr@nhlbi.nih.gov.

Current Author Addresses: Dr. Shah: Division of Cardiovascular Sciences of the National Heart, Lung, and Blood Institute, 6701 Rockledge Drive, Room 8174, Bethesda, MD 20892-7956.

Dr. Lauer: National Institutes of Health, 1 Center Drive, Building 1, Room 144, Bethesda, MD 20814.

Author Contributions: Conception and design: M.R. Shah, M.S. Lauer.

Drafting of the article: M.R. Shah, M.S. Lauer.

Critical revision of the article for important intellectual content: M.S. Lauer.

Final approval of the article: M.R. Shah, M.S. Lauer.

Ann Intern Med. 2016;164(2):125-126. doi:10.7326/M15-2587
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Recent clinical trials found that, compared with an angiotensin-converting enzyme inhibitor, angiotensin-receptor blocker and neprilysin inhibitor combination therapy decreased cardiovascular mortality in patients with heart failure with reduced ejection fraction. The authors discuss the importance of these findings.


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