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Transmission of Hepatitis E Virus by Plasma Exchange: A Case Report

Vincent Mallet, MD, PhD; Rebecca Sberro-Soussan; Anais Vallet-Pichard, MD; Anne-Marie Roque-Afonso, MD, PhD; and Stanislas Pol, MD, PhD
[+] Article, Author, and Disclosure Information

This article was published at www.annals.org on 1 March 2016.

From Université Paris Descartes, Assistance Publique-Hôpitaux de Paris, Groupe Hospitalier Cochin Port Royal, Institut Pasteur, Unité Mixte de Service 020, Paris, France; Assistance Publique-Hôpitaux de Paris, Hôpital Necker Paris, France; Assistance Publique-Hôpitaux de Paris, Groupe Hospitalier Cochin Port Royal, Institut Pasteur, Unité Mixte de Service 020, Paris, France; Université Paris Sud, Assistance Publique-Hôpitaux de Paris, Institut National de la Santé et de la Recherche Médicale unité 1193, Villejuif, France.

Disclaimer: The Agence Nationale de la Recherche paid for the serologic tests conducted during the study.

Acknowledgment: The authors thank the patient for her altruistic decision to allow this article to focus on her case, with a view to helping others. The authors also thank Drs. Corouge and Bererhi for caring for the patient and Drs. Hauser and Beyloune (Etablissement Français du Sang) for performing the transfusional investigation.

Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=L15-0502.

Ann Intern Med. 2016;164(12):851-852. doi:10.7326/L15-0502
© 2016 American College of Physicians
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Grahic Jump Location

ALT levels after renal transplantation (top) and phylogenetic analysis (bottom).

The phylogenetic analysis was conducted on the Molecular Evolutionary Genetics Analysis (MEGA) software version 6 (www.megasoftware.net) using the Neighbor–Joining method from a Kimura 2-parameter distance matrix based on partial nucleotide sequences of open reading frame 1. Sequences are indicated by their GenBank accession number. The black diamonds indicate the sequences described in the case report. ALT = alanine aminotransferase; HEV = hepatitis E virus.

Grahic Jump Location




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