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When the Gold Standard Loses Its Luster, Perhaps It Is Time to Change NomenclatureWhen the Gold Standard Loses Its Luster, Is It Time to Change Nomenclature?

Alexander Borowsky, MD; and Laura Esserman, MD, MBA
[+] Article, Author, and Disclosure Information

This article was published at www.annals.org on 22 March 2016.

From University of California, Davis, Davis, California, and UCSF Medical Center, San Francisco, California.

Disclosures: Disclosures can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M16-0526.

Requests for Single Reprints: Alexander Borowsky, MD, Center for Comparative Medicine, University of California, Davis, County Road 98 and Hutchinson Drive, Davis, CA 95616; e-mail, adborowsky@ucdavis.edu.

Current Author Addresses: Dr. Borowsky: Center for Comparative Medicine, University of California, Davis, County Road 98 and Hutchinson Drive, Davis, CA 95616.

Dr. Esserman: Department of Surgery, UCSF Medical Center, 1600 Divisadero Street, Box 1710, San Francisco, CA 94115.

Ann Intern Med. 2016;164(10):694-695. doi:10.7326/M16-0526
© 2016 American College of Physicians
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A report from the B-Path (Breast Pathology) study reveals problems with the gold standard for breast cancer diagnosis. The data show significant interpretation discordance. The editorialists discuss the implications of diagnostic uncertainty.


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