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Update in Critical Care Medicine: Evidence Published in 2015Update in Critical Care Medicine

Nathan E. Brummel, MD, MSCI; and E. Wesley Ely, MD, MPH
[+] Article, Author, and Disclosure Information

From Vanderbilt University School of Medicine and Department of Veterans Affairs Medical Center, Tennessee Valley Healthcare System, and Geriatric Research, Education and Clinical Center, Nashville, Tennessee.

Disclaimer: The contents of this paper are solely the responsibility of the authors and do not necessarily represent those of the U.S. government, the U.S. Department of Veterans Affairs, the National Institutes of Health, or Vanderbilt University.

Grant Support: From the National Institutes of Health (awards KL2TR000446, R03AG040549, R01AG035117 and R01HL111111), Department of Veterans Affairs Tennessee Valley Health Care System Geriatric Research, Education and Clinical Center (GRECC). These funding sources had no role in the design and conduct of the study; collection, analysis, and interpretation of the data; preparation, review, or approval of the manuscript; and decision to submit the manuscript for publication.

Disclosures: Dr. Brummel reports grants from National Institutes of Health during the conduct of the study. Dr. Ely reports grants from National Institutes of Health and other support from Department of Veterans Affairs, Tennessee Valley Healthcare System GRECC during the conduct of the study, as well as other support from Abbott, Pfizer, Orion, Hospira outside the submitted work. Forms can be viewed at www.acponline.org/authors/icmje/ConflictOfInterestForms.do?msNum=M16-0572.

Editors' Disclosures: Christine Laine, MD, MPH, Editor in Chief, reports that she has no financial relationships or interests to disclose. Darren B. Taichman, MD, PhD, Executive Deputy Editor, reports that he has no financial relationships or interests to disclose. Cynthia D. Mulrow, MD, MSc, Senior Deputy Editor, reports that she has no relationships or interests to disclose. Deborah Cotton, MD, MPH, Deputy Editor, reports that she has no financial relationships or interest to disclose. Jaya K. Rao, MD, MHS, Deputy Editor, reports that she has stock holdings/options in Eli Lilly and Pfizer. Sankey V. Williams, MD, Deputy Editor, reports that he has no financial relationships or interests to disclose. Catharine B. Stack, PhD, MS, Deputy Editor for Statistics, reports that she has stock holdings in Pfizer and Johnson & Johnson.

Requests for Single Reprints: Nathan E. Brummel, MD, MSCI, Vanderbilt University School of Medicine, Suite 350, 2525 West End Avenue, Nashville, TN 37203; e-mail, nathan.brummel@vanderbilt.edu.

Current Author Addresses: Dr. Brummel: Vanderbilt University School of Medicine, Suite 350, 2525 West End Avenue, Nashville, TN 37203.

Dr. Ely: VA Tennesse Valley Healthcare System Geriatric Research, Education and Clinical Center (GRECC), and Department of Medicine, Vanderbilt School of Medicine, Nashville, TN 37232-8300.

Author Contributions: Conception and design: N. Brummel, E.W. Ely.

Analysis and interpretation of the data: N. Brummel, E.W. Ely.

Drafting of the article: N. Brummel, E.W. Ely.

Critical revision for important intellectual content: N. Brummel, E.W. Ely.

Final approval of the article: N. Brummel, E.W. Ely.

Obtaining of funding: N. Brummel, E.W. Ely.

Collection and assembly of data: N. Brummel, E.W. Ely.


Ann Intern Med. 2016;164(9):W15-W20. doi:10.7326/M16-0572
© 2016 American College of Physicians
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This Update summarizes studies published in 2015 that the authors consider highly relevant to the practice of critical care medicine.

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