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Crohn Disease: A Hopeful Note

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Department of Medicine, School of Medicine, Case Western Reserve University; Cleveland, Ohio

Ann Intern Med. 1981;95(6):777-778. doi:10.7326/0003-4819-95-6-777
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Physicians who treat patients with Crohn disease should take heart. Recent studies suggesting indications for and efficacy of various therapies for the disease are remarkable, considering that knowledge of its cause has not as yet moved very far beyond the killer lymphocyte stage (1) and shows no signs of early progress therefrom.

Therapy in Crohn disease should be tailored to the stage of the disorder. Although detailed staging techniques have been developed (2, 3), they are almost too clumsy for use in daily practice where a simpler classification is preferable. Thus, patients can usually be assigned to one of three


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