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Long-Term Follow-up of Voluntary Ingestion of Helicobacter pylori

Arthur J. Morris, BSc, MBChB; M. Rafiq Ali, MBChB; Gordon I. Nicholson, MBChB; Guillermo I. Perez-Perez, DSc; and Martin J. Blaser, MD
[+] Article and Author Information

Grant Support: In part by the Medical Research Service of the Veterans Administration and by the Proctor and Gamble Company.

Requests for Reprints: Arthur J. Morris, MD, Microbiology Laboratory, Duke University Medical Centre, Box 3879, Durham, NC 27710.

Current Author Addresses: Dr. Morris: Microbiology Laboratory, Duke University Medical Centre, Box 3879, Durham, NC 27710.

Dr. Ali: Department of Gastroenterology, Middlemore Hospital, Otahuhu, Auckland, New Zealand.

Dr. Nicholson: Department of Gastroenterology, Auckland Hospital, Park Road, Auckland, New Zealand.

Drs. Perez-Perez and Blaser: Department of Medicine, Division of Infectious Diseases, Vanderbilt University Medical Center, A-4321, Medical Center North, Nashville, TN 37232-2605.


Ann Intern Med. 1991;114(8):662-663. doi:10.7326/0003-4819-114-8-662
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This excerpt has been provided in the absence of an abstract.

In 1985, Barry Marshall reported his ingestion of Helicobacter pylori (previously known as Campylobacter pylori [1]). He developed an acute, but self-limited, histologic gastritis (2). In 1987, Morris and Nicholson (3) reported the case of another volunteer who ingested H. pylori. Although the volunteer had symptoms for only 10 days, both the infection and histologic gastritis persisted until day 67 when 1 month of treatment with bismuth subsalicylate was begun. A biopsy specimen obtained 1 week after completing therapy, on day 103, showed the apparent eradication of H. pylori and the almost complete resolution of histologic gastritis (3). We report

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