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Predicting Bacteremia |

Predicting Bacteremia

Leonard Leibovici, MD
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Tel Aviv University
Petah Tiqva 49100, Israel

Ann Intern Med. 1991;114(8):703. doi:10.7326/0003-4819-114-8-703_1
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To the editors: Two points in the article by Bates and colleagues (1) merit reconsideration. First, rapidly fatal disease was included in the final model as a significant and independent predictor of true bacteremia. However, "true bacteremia" was defined by reviewers who were not blinded to the outcome of the episode (whether or not the patient "had done well"). If the original assessment of a rapidly fatal disease was accurate, than "true bacteremia" was defined with foreknowledge of a factor (outcome of the patient) closely related to one of the independent variables. Thus, a strong bias may have been introduced




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