Anxiety disorders have been the neglected stepchild of primary care–based mental health care. Compared with the extensive research in primary care on the adverse effects of depression on somatic symptom burden, decrements in function, and medical utilization and costs (1–2), far less research has been completed on anxiety disorders. Yet, the National Comorbidity Survey (3) has shown that anxiety disorders are the most frequent disorders in the general population and are associated with substantial social and vocational impairment. Primary care patients with anxiety disorders are high users of primary care services and have many medically unexplained symptoms (that is, chest pain and rapid heart rate), clinically significant decrements in function, and high medical costs (1, 4–6). They also have high levels of psychiatric comorbidity, particularly major depression. Meeting Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV), criteria for 1 or more anxiety disorder markedly increases the risk for major depression over the following year (7). Anxiety disorders are also associated with adverse health behaviors, such as smoking and sedentary lifestyle (8–9), which may contribute to the high levels of medical comorbidity found in adults with anxiety disorders.