Patients, their family and friends, and medical professionals often consider the experiences of illness (and particularly terminal illness) as primarily physical, emotional, and spiritual. This is no doubt true, but for at least some segment of the patient population, their intellects, or intellectual lives, offer ways to frame and confront the complexity of the experiences of illness and dying, to consider the meaning of their lives, and to remember that they are more than their diseases. For these patients, the habits of the life of the mind, a life centered on gaining and sharing knowledge, are familiar and comfortable: They are accustomed to defining, analyzing, and assessing complex situations; they have a faith in knowledge and their intellectual abilities. Confronted with the illness and mortality of the body, such patients may find that these intellectual frameworks offer a way to make sense of these new experiences, to integrate them within their bodies of knowledge.