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Chronic Ulcerative Colitis

HORACE W. SOPER
Ann Intern Med. 1927;1(5):313-350. doi:10.7326/0003-4819-1-5-313
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Under the term colitis we consider the ordinary catarrhal form as well as the chronic ulcerative type. Chronic ulcerative colitis must be differentiated from tuberculosis, syphilis, post dysenteric ulcers and polyposa intestinalis adenomatosa.

Chronic ulcerative colitis has been a medical problem for many years. It has been designated idiopathic, non-specific, post-bacillary, infectious and septic ulcerative colitis. It appears to have been described as a disease entity by Wilke and Moxon (1) in 1875 and White (2) in 1888. There has been a great deal of difference of opinion as to the etiology of the disease. Logan and his co-workers considered

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