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Ann Intern Med. 1928;1(8):621-623. doi:10.7326/0003-4819-1-8-621
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The experimental attack upon the etiological problem of gastric ulcer has led to no conclusive results. Experimentally-produced ulcers, no matter by what form of local injury they have been developed, have all differed essentially from human ulcers in that they usually quickly heal, while in man gastric ulcer is characterized essentially by its markedly chronic course. Further, the effects of local trauma to the gastric mucosa vary greatly in different animals; no one of the causes adduced for ulcer production is constant in its action, and, so far as man is concerned, no etiological entity can be shown to exist



peptic ulcer

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