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General Tuberculin-like Reactions in Rheumatic Fever Patients Following Intravenous Injection of Streptococcus Vaccines or Nucleoproteins.

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BySWIFT HOMER F., HITCHCOCK CHARLES H., DERICK CLIFFORD L..  (Proc. Soc. Exper. Biol. and Med.. January1928; , p. 312.).

Ann Intern Med. 1928;1(8):627-628. doi:10.7326/0003-4819-1-8-627_2
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Some years ago Swift suggested that rheumatic fever had many points of similarity with tuberculosis. Since then it has been shown by him and his associates that rabbits may be rendered hypersensitive to streptococci by the production of focal lesions with various types of hemolytic streptococci isolated from rheumatic fever and other diseases. As these streptococci have been shown to belong to various immunological groups the hypothesis was formulated that if they had any etiologic relationship with the disease it was because of a peculiar type of tissue activity acquired by the rheumatic patient. They have, therefore, tested the reactivity


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