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Experimental Study of Acquired Resistance of the Rabbit's Renal Epithelium to Uranyl Nitrate

Ann Intern Med. 1928;1(10):747-789. doi:10.7326/0003-4819-1-10-747
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The ability of renal cells to regenerate after injury is scarcely mentioned in most textbooks of medicine. That these cells must have a remarkable regenerative power is best seen in the kidneys of individuals recovering from scarlet fever in which later examination will often reveal no evidence of previous damage, indicating complete restitution of damaged epithelium. The same thing occurs in the varying degrees of nephrosis accompanying many acute infections. It is also true that some cellular regeneration takes place after injury by metallic salts or other chemicals which act on the kidney.

A question which has received even less


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