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Two Years' Experience with the Malarial Treatment of General Paralysis in a State Institution. Clinical, Serological and Autopsy Observation in 100 cases.

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By Bahr Max A., Bruetsch W. L..  Central State Hospital, Indianapolis, Indiana (Amer. Jour. of Psychiatry. , Vol. VII:, March, 1928; , p. 715.).

Ann Intern Med. 1928;1(11):939. doi:10.7326/0003-4819-1-11-939_1
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Of 100 general paralytic patients treated with malaria, 25 were able to leave the hospital. Twelve patients improved to such a degree that they can be trusted in an useful occupation in the hospital. Forty patients are placed in the unimproved group. In 32 patients of the latter group the disease is progressing. In 8 instances the disease has remained stationary. Five patients succumbed during the rigors and 18 died following the malaria. Serological changes following malarial treatment occurred in both the improved and the unimproved groups. While there was no parallelism between the degree of clinical and serological improvement


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