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Agranulocytic Angina with Thrombopenic Purpura

Ann Intern Med. 1928;2(6):542-544. doi:10.7326/0003-4819-2-6-542
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Since Schultz' (1) report in 1922 of the condition since known as agranulocytic angina, the recognition of this disastrous malady is becoming steadily more frequent both in Germany and in this country. A year ago Kastlin (2) reviewed 43 cases and since his report, cases have been reported by Finnigan (3), Hart (4), Carnot (5), two by Linthicum (6), Ashworth and Maphis (7), Gundrum (8), Whitehead (9), and Sachs (10), making a total of 52 cases.

The onset is abrupt with sore throat, high fever, chilliness, general aching, prostration, headache, and sometimes vomiting. Herpes may appear and half the cases


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