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Hepalic Lesion in Eclampsia: An Experimental Study.

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By Dieckmann William J..  (Proc. of the Soc. f. Exper. Biol. and Med.. , December, 1928; , p. 239.).


Ann Intern Med. 1929;2(8):834-835. doi:10.7326/0003-4819-2-8-834
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The hepatic lesion in human eclampsia is peculiar in that it does not occur in any pregnant animal or in any other human disease. The lesion is essentially a thrombosis occurring in the capillaries of the portal vein in the periphery of the liver lobule with hemorrhage into the adjacent tissues, resulting in necrosis. Dieckmann believes that whatever the substance is which causes this thrombosis, it must be in greater concentration in the portal system. From clinical experience it is known that curtailment of protein together with intestinal elimination will in almost all cases prevent eclampsia. We also know that

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