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Hemorrhagic Glomerular Lesions Produced by Filtrates of Streptococcus Viridans Cultures.

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By Rich Arnold R., Bumstead John H., Frobisher Martin Jr..  (Proc. of the Soc. for Exper. Biology and Med.. , February, 1929; , p. 397.).

Ann Intern Med. 1929;2(11):1229-1230. doi:10.7326/0003-4819-2-11-1229
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It is well known that hemorrhagic glomerulonephritis occurs with great frequency in association with Streptococcus viridans infections, especially with endocarditis caused by this organism. The glomerular changes in the latter affection are generally regarded as a direct result of damage caused by minute emboli from the vegetations on the heart valves. This explanation was doubted by the workers named above for the following reason: If the nephritis associated with Streptococcus viridans endocarditis is merely the result of emboli, one might reasonably expect to encounter a similar nephritis quite as commonly in every form of endocarditis characterized by profuse, friable vegetations


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