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Adrenalin in Malaria

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Quirigua Hospital, United Fruit Co., Puerto Barrios, Guatemala

Ann Intern Med. 1929;2(12):1343-1345. doi:10.7326/0003-4819-2-12-1343
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I know of no literature regarding the use of adrenalin in the treatment of pernicious malaria but have noted the beneficial clinical results obtained by Doctor N. P. Macphail, who has used it rather extensively in cases of persistent nausea and vomiting incident to severe malaria infection.

In pernicious attacks, whether of the cerebral, algid or paratyphoid types, sluggish reactions from the use of quinine, intramuscularly, or orally, supplemented by subcutaneous injections of adrenalin chloride in doses of from 8 to 15 minims, it is frequently followed by an acute exacerbation of the symptoms; and though parasites could not be



epinephrine ; malaria

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