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Attempted Production of Vaccinal Encephalitis in Rabbits with a Testicular Virus.

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By THOMPSON RICHARD.  (Proc. Soc. f. Exper. Biology and Medicine. , 1929; , XXVI:, p. 559.).


Ann Intern Med. 1929;3(3):284-285. doi:10.7326/0003-4819-3-3-284
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The reproduction of vaccinal encephalitis in rabbits is of interest at this time chiefly in view of the prevalence of postvaccinal encephalitis in some European countries. The possible use of the rabbit's brain as a medium for mass production of sterile vaccine (advocated by Levaditi) also adds importance to the question. A considerable number of European workers have succeeded in producing what they regard as a vaccinal encephalitis in rabbits. Levaditi and his co-workers since 1921 have developed a strain of vaccine virus known as neurovaccine which produces regularly on intracerebral injection into rabbits a typical encephalitis with paralytic symptoms

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