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Ann Intern Med. 1930;3(10):1008-1023. doi:10.7326/0003-4819-3-10-1008
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Agranulocytosis, Agranulocytic Angina or Malignant Neutropenia was first described in full in the German literature by W. Schultz in 1922. Since this report a total of about eighty papers have been written describing this condition. The first appearance in American literature was in the paper of W. A. Moore and H. S. Wieder in the Journal of the American Medical Association, August 1925.

Schilling says: "the term 'agranulocytosis' has come into the nomenclature on account of its brevity. It is incorrect: the name of 'Agranulocytes' was originally chosen for 'neutrophiles without granulations' of leukaemias. By 'Agranulocytosis' is meant an increase


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