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Investigations as to the Place of the Liver in the Intermediary Metabolism.

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By PASCHKIS KARL.  (Klin. Wschr.. , October11 , 1930.).

Ann Intern Med. 1930;4(5):508. doi:10.7326/0003-4819-4-5-508_1
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The rôle played by the liver in protein metabolism remains still an unsolved problem. The protein material of the food is either wholly or for the greater part broken down in the intestine to the simple fundamentals, the amino-acids, and carried in this form through the portal vein to the liver. It is a question whether desaminization of the amino-acids is one of the functions of the liver, or whether this process occurs in the peripheral tissues. Van Slyke, Folin, and Denis hold different views on this matter. Mann and Magath have proved experimentally than the dog deprived of his



metabolism ; liver

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