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The Relation of Endemic Goiter to Mental Deficiency

Ann Intern Med. 1930;4(6):569-577. doi:10.7326/0003-4819-4-6-569
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Endemic goiter has occupied a prominent place in medical literature from the time of our earliest medical writings. We also find references to this age old disease in our ancient manuscripts.

We have definite records of cretins since early Roman history, but it was not until the beginning of the 16th century that the Swiss physician, Paracelsus, described cretinism in detail and emphasized the relation of cretinism to endemic goiter. In 1800, appeared Fodere's basic essay on "Goiter and Cretinism", in which he states that "Goiter is the first degree of a degenerative process in which cretinism is the last


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