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Studies on the Etiology of Rheumatoid Arthritis. I. Bacteriological Investigations on Blood, Synovial Fluid, and Subcutaneous Nodules in Rreumatoid Arthritis.

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By DAWSON M. H., OLMSTEAD MIRIAM, BOOTS R. H..  (Proc. of the Soc. f. Exper. Biol. and Med.. , January, 1931; , p. 419.).


Ann Intern Med. 1931;4(9):1227-1228. doi:10.7326/0003-4819-4-9-1227_2
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The clinical evidence pointing to an infective origin of rheumatoid arthritis has led numerous investigators to seek a bacterial agent to which etiological significance could be ascribed. A great variety of such agents has been reported, but lack of uniformity in the results obtained has confused the issue. Cecil, Nicholls, and Stainsby, by the use of a special technique, claim to have demonstrated the presence of streptococci in the blood stream in 61.5 per cent of a series of 78 cases examined. Because of the unusual nature of this report and the importance of their findings, the present investigation was

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