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Studies on the Etiology of Rheumatoid Arthritis. II. Agglutination Reactions with Hemolytic Streptococci in Rheumatoid Arthritis.

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By DAWSON M. H., OLMSTEAD MIRIAM, BOOTS R. H..  (Proc. of Soc. f. Exper. Biol. and Med.. , January, 1931; , p. 421.).

Ann Intern Med. 1931;4(9):1228. doi:10.7326/0003-4819-4-9-1228
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The bacteriological investigations on the blood, synovial fluid and subcutaneous nodules in rheumatoid arthritis reported by those investigators entirely failed to confirm the results reported by Cecil, Nicholls, and Stainsby. The latter had, however, further reported that the sera of patients suffering from rheumatoid arthritis possessed the property of agglutinating their "typical strains" to a remarkably high titre. Through the courtesy of Dr. Cecil several "typical strains" were made available. Specimens of serum were obtained from a large number of patients suffering from rheumatoid arthritis and agglutination tests were done using these strains as agglutinogens. For control purposes a large


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