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Gland Extracts in Experimental Carcinoma and Sarcoma of Albino Rats

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Research and Biological Laboratories, Parke, Davis and Company, Detroit, Michigan

Ann Intern Med. 1931;4(12):1589-1597. doi:10.7326/0003-4819-4-12-1589
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Recent publications directed to the possible beneficial effect of organ extracts in cancer, have led us to evaluate a number of these extracts in experimental carcinoma and sarcoma of rats.

EXPERIMENTAL: A series of albino rats were inoculated with the Flexner-Jobling carcinoma* or Jensen sarcoma* of rats. When the tumor reached in size about one square centimeter, the animals were divided into three groups and placed under treatment. One group was treated with the hormone extract; the second group remained as untreated controls and the third group was placed on treatment with an extract of oxen testis prepared in a


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