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Bacteriological Investigations on the Blood, Synovial Fluid and Subcutaneous Nodules in Rheumatoid (Chronic Infectious) Arthritis.

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By DAWSON MARTIN H.. , M.D., OLMSTEAD MIRIAM. , A.M., and BOOTS RALPH H.. , M.D. (Arch. Int. Med.. , 1932; , xlix:, 173.-180.)


Ann Intern Med. 1932;5(10):1324-1325. doi:10.7326/0003-4819-5-10-1324_3
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In this study the term 'rheumatoid arthritis' is used to designate that form of chronic multiple arthritis more commonly called 'chronic infectious' or 'atrophic arthritis. One hundred and five blood cultures, the majority in duplicate, were carried out on 80 patients suffering from rheumatoid arthritis, according to the technic of Cecil, Nicholls and Stainsby. As control material, 31 samples of blood from normal persons and 16 samples of sterile agar were subjected to similar manipulations. The blood cultures from patients suffering with rheumatoid arthritis failed to yield organisms that would be considered of etiologic significance. No significant difference was observed

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