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The Present Status of BCG Vaccination.

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By PETROFF S. A.. , Ph.D. (The New Engl. Jr. of Med.. , 1932; , ccvi:, 436.-439.)

Ann Intern Med. 1932;5(11):1441-1442. doi:10.7326/0003-4819-5-11-1441_2
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No problem in tuberculosis, since the famous controversy on the entity of bovine and human tuberculosis some twenty-five years ago, has created such a feverish discussion as the prophylactic immunization against tuberculosis known as BCG vaccination. From study of three different cultures of BCG, obtained at different times and from three different sources, the last directly from Professor Calmette, Petroff came to the conclusion that BCG was an organism of low virulence, producing tuberculous changes which had the tendency to heal. But with each of the three cultures, a small number of animals which had been under observation for about


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