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The Occurrence of Sicklemia in the White Race.

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By ROSENFELD SAMUEL. , M.D., and PINCUS JOSEPH B.. , M.D. (Am. Jr. Med. Sc.. , 1932; , clxxxiv:, 674.-682.)


Ann Intern Med. 1932;6(6):843. doi:10.7326/0003-4819-6-6-843_1
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It is generally believed that sickle cells occur only in the blood of the negro or in those with an admixture of negro blood. The incidence of the sickling trait among unselected negroes seems to be about 7 per cent. This trait is hereditary and is transmitted as a Mendelian dominant. The literature alleging the occurrence of sicklemia in white persons has been reviewed, keeping in mind that the chief sources of error lie in mistaking other deformities of the red blood cells for sickling or in failure to exclude the possibility of admixture of negro blood in cases with

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