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On the Transmission of Huntington's Chorea for 300 Years—the Bures Family Group.

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By VESSIE P. R.. , M.D. (Jr. Nerv. and Ment. Dis.. , 1932; , lxxvi:, 553.-573.)


Ann Intern Med. 1932;6(6):843. doi:10.7326/0003-4819-6-6-843_2
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Through study of the earliest colonial records the author has ascertained that a group which emigrated from Bures, Suffolk, England, in 1630, has contributed very largely to the incidence of hereditary chorea in this country. Approximately 1,000 cases of Huntington's chorea have been collected from the direct and collateral lines of this group which consisted of three men and their wives. The social problems of this group and their more immediate descendants show why the choreic affliction was reputed disgraceful and viewed with terror in succeeding generations. The witchcraft literature and records of court procedures indicate the extent to which

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