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Ann Intern Med. 1935;9(3):350-352. doi:10.7326/0003-4819-9-3-350
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To Kaznelson's original suggestion of nineteen years ago, that splenectomy is a curative measure in thrombopenic purpura, little more has been added. The disorder, as earlier, retains its main divisions, as occurring in a primary or idiopathic form, and in a symptomatic variety secondary to other disorders. Although we are essentially concerned with the primary form, the existence of the secondary form is of the utmost diagnostic importance for the reason that in this secondary form splenectomy is not only contraindicated but may be actually harmful. The conditions most frequently giving rise to symptomatic purpura are sepsis, infectious diseases, drug




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