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Ann Intern Med. 1944;20(2):340-343. doi:10.7326/0003-4819-20-2-340
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Encephalitis in man may be caused by any one of several different agents. It may occur as a complication or unusual manifestation of a number of virus infections (such as measles, vaccinia, anti-rabies inoculation) in which tissues other than the nervous system are primarily involved. In other types of infection, however, the virus is fundamentally neurotropic, and manifestations of encephalitis dominate the clinical picture. Of these, the well established forms occurring in the United States are the Economo and St. Louis types of encephalitis, and the Eastern and Western types of "equine" encephalomyelitis.

The etiological agent and mode of transmission




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